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DeCS
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Descriptor English:
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AlkB Homolog 4, Lysine Demethylase
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Descriptor Spanish:
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Homólogo 4 de Alkb Lisina Desmetilasa
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Descriptor Portuguese:
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Homólogo AlkB 4 da Lisina Desmetilase
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Synonyms English:
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Alkylated DNA Repair Protein AlkB Homolog 4
Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
Alpha Ketoglutarate Dependent Dioxygenase Alkb Homolog 4
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Tree Number:
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D08.811.682.662.582.138
D08.811.682.690.416.139.937
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Definition English:
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A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56501
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Unique Identifier:
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D000071501
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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